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U.S. Route 278 (US 278) is a parallel route of US 78. It currently runs for from
Hilton Head Island, South Carolina Hilton Head Island, sometimes referred to as simply Hilton Head, is a South Carolina Lowcountry, Lowcountry resort town and barrier island in Beaufort County, South Carolina, United States. It is northeast of Savannah, Georgia, and southwest of C ...
, to
Wickes, Arkansas Wickes is a city in Polk County, Arkansas, Polk County, Arkansas, United States. The population was 754 at the 2010 census. Near Wickes is the Boggs Springs Youth Encampment of the American Baptist Association, a retreat of Missionary Baptist chur ...
at US 71/ US 59, passing through five states in the process. Landmarks along its route include the
Department of Energy A Ministry of Energy or Department of Energy is a government department in some countries that typically oversees the production of fuel and electricity; in the United States, however, it manages nuclear weapons development and conducts energy-rel ...
's
Savannah River Site The Savannah River Site (SRS) is a U.S. Department of Energy (DOE) reservation in the United States in the state of South Carolina, located on land in Aiken, Allendale, and Barnwell counties adjacent to the Savannah River, southeast of August ...
in South Carolina and the Tennessee-Tombigbee Waterway in eastern Mississippi. There are several universities located along the highway including
Georgia State University Georgia State University (Georgia State, State, or GSU) is a Public university, public research university in Atlanta, Atlanta, Georgia. Founded in 1913, it is one of the University System of Georgia's four research universities. It is also the ...
, the
University of Mississippi The University of Mississippi (byname Ole Miss) is a public research university that is located adjacent to Oxford, Mississippi, and has a medical center in Jackson. It is Mississippi's oldest public university and its largest by enrollment. ...
, and the
University of Arkansas at Monticello The University of Arkansas at Monticello (UAM) is a public university in Monticello, Arkansas with Colleges of Technology in Crossett and McGehee. UAM is part of the University of Arkansas System and offers master's degrees, baccalaureate degrees ...
.


Route description


Arkansas

US 278 begins at an intersection with US 59/ US 71 in the town of
Wickes Wickes is a home improvement retailer and garden centre, based in the United Kingdom with more than 230 stores throughout the country. Its main business is the sale of supplies and materials, for homeowners and the building trade. It is listed ...
in southwestern Arkansas. From Wickes, US 278 continues eastward near
Gillham Lake Gillham Lake is a small reservoir located along the Cossatot River, mostly in Howard County, but also extending westward into Polk County, Arkansas. The lake is from Gillham, Arkansas. Recreation The Flood Control Act of 1958 approved the lake f ...
to an overlap with US 70 through Dierks. Continuing south, US 278 overlaps Highway 26 for at Center Point. Further south the route continues into
Nashville Nashville is the capital city of the U.S. state of Tennessee and the seat of Davidson County. With a population of 689,447 at the 2020 U.S. census, Nashville is the most populous city in the state, 21st most-populous city in the U.S., and the ...
. The route overlaps US 371 and later
Highway 27 Route 27, or Highway 27, may refer to: Australia * Burke Developmental Road (Queensland) * Zeehan Highway (Tasmania) Canada * Alberta Highway 27 * British Columbia Highway 27 * Manitoba Highway 27 * Prince Edward Island Route 27 * Saskatchewan ...
upon entering Nashville. Entering
Hempstead County Hempstead County is a county located in the U.S. state of Arkansas. As of the 2010 census, the population was 22,609. As of the 2020 census, the population decreased to 20,065. The county seat is Hope. Hempstead County is Arkansas's fourth cou ...
, the highway winds through rural areas to Ozan and
Washington Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on ...
, before meeting US 278 Business (US 278B) outside
Hope Hope is an optimistic state of mind that is based on an expectation of positive outcomes with respect to events and circumstances in one's life or the world at large. As a verb, its definitions include: "expect with confidence" and "to cherish ...
. The highway crosses over
Interstate 30 Interstate 30 (I-30) is a Interstate Highway in the southern states of Texas and Arkansas in the United States. I-30 travels from I-20 west of Fort Worth, Texas, northeast via Dallas, and Texarkana, Texas, to I-40 in North Little Rock, Ar ...
(I-30) shortly after entering the city limits and overlaps Highway 29 and
Highway 32 The following highways are numbered 32: International * Asian Highway 32 * European route E32 Australia * Great Western Highway * Barrier Highway * East Derwent Highway * Mitchell Highway Canada * Alberta Highway 32 * Manitoba Highway 32 * N ...
. US 278/AR 29/AR 32 intersect
US 67 U.S. Route 67 is a major north–south U.S. highway which extends for 1,560 miles (2,511 km) in the Central United States. The southern terminus of the route is at the United States-Mexico border in Presidio, Texas, where it continues so ...
in east Hope. South of this junction AR 29 splits and US 278/AR 32 continues southeast. Further along this route, AR 32 turns southeast to Willisville and US 278 runs toward Camden. The route intersects Highway 53 in rural Nevada County, overlaps US 371 in Rosston, and has a junction with Highway 57 upon entering Ouachita County. In Camden, US 278 intersects
Highway 24 Route 24, or Highway 24, can refer to: International * European route E24 Australia * Lyell Highway (Tasmania) * Central Arnhem Road, NT Austria * Verbindungsspange Rothneusiedel Canada * Alberta Highway 24 * British Columbia Highway 24 * Ma ...
before it meets US 278B and US 79B prior to overlapping
US 79 U.S. Route 79 (US 79) is a United States highway in the Southern United States. The route is officially considered and labeled as a north-south highway, but its path is actually more of a diagonal northeast-southwest highway. The highway's nort ...
. US 278 breaks from US 79 near Harrell Field shortly before entering East Camden. US 278 continues into
Calhoun County Calhoun County is the name of several counties in the United States of America named after U.S. Vice President John C. Calhoun: * Calhoun County, Alabama * Calhoun County, Arkansas * Calhoun County, Florida * Calhoun County, Georgia * Calhoun Cou ...
and
Hampton Hampton may refer to: Places Australia *Hampton bioregion, an IBRA biogeographic region in Western Australia *Hampton, New South Wales *Hampton, Queensland, a town in the Toowoomba Region *Hampton, Victoria Canada *Hampton, New Brunswick *Hamp ...
and a junction with
US 371 U.S. Route 371 is a north–south United States highway in the U.S. states of Arkansas and Louisiana. The highway's northern terminus is in De Queen, Arkansas at an intersection with U.S. Highway 70. It is co-signed for its last between Lo ...
. The east edge of town brings an intersection with Highway 274 as US 278 continues to Harrell and Highway 160 before entering Bradley County. Aside from
Banks A bank is a financial institution that accepts deposits from the public and creates a demand deposit while simultaneously making loans. Lending activities can be directly performed by the bank or indirectly through capital markets. Because ...
, where US 278 has a junction with Highway 275, the route runs through rural country until
Warren A warren is a network of wild rodent or lagomorph, typically rabbit burrows. Domestic warrens are artificial, enclosed establishment of animal husbandry dedicated to the raising of rabbits for meat and fur. The term evolved from the medieval Angl ...
, where US 278 almost entirely bypasses the city to the south while US 278B runs downtown, including a brief overlap with
US 63B The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
. US 278 has an intersection with US 63/ AR 8 along the southern edge of Warren before serving as the eastern terminus for US 278B. Further east the highway intersects Highway 172, which gives access to the Warren Prairie Natural Area just east of the
Drew County Drew County is a county located in the southeast region of the U.S. state of Arkansas. As of the 2010 census, the population was 18,509, making it the 39th most populous of Arkansas's 75 counties. The county seat and largest city is Monticello. ...
line. The route continues to
Monticello Monticello ( ) was the primary plantation of Founding Father Thomas Jefferson, the third president of the United States, who began designing Monticello after inheriting land from his father at age 26. Located just outside Charlottesville, V ...
to McGehee, where it meets US 65. US 278 overlaps US 65 southward for until they separate in Lake Village. There, US 65 splits off and US 278 overlaps US 82 east to the
Mississippi River The Mississippi River is the second-longest river and chief river of the second-largest drainage system in North America, second only to the Hudson Bay drainage system. From its traditional source of Lake Itasca in northern Minnesota, it f ...
, where US 82/US 278 crosses into Mississippi. Long-term plans are to move US 278 to the
Charles W. Dean Bridge The Charles W. Dean Bridge, known before 1999 as the Great River Bridge, is a planned cable-stayed bridge to carry Interstate 69 and U.S. Route 278 across the Mississippi River between Arkansas City, Arkansas and Benoit, Mississippi. The Arka ...
, which is part of the proposed extension of
I-69 Interstate 69 (I-69) is an Interstate Highway in the United States currently consisting of 10 unconnected segments with an original continuous segment from Indianapolis, Indiana, northeast to the Canadian border in Port Huron, Michigan, at ...
.


Mississippi

US 82/US 278 goes through Greenville to Leland, where US 278 separates from US 82 at US 61. US 278 then joins US 61 northward through
Cleveland Cleveland ( ), officially the City of Cleveland, is a city in the U.S. state of Ohio and the county seat of Cuyahoga County. Located in the northeastern part of the state, it is situated along the southern shore of Lake Erie, across the U.S. ...
before splitting in Clarksdale. East of Clarksdale, it overlaps
Mississippi Highway 6 Mississippi Highway 6 (MS 6) runs east–west from MS 161 in Lyon, east to MS 25 near Amory. It travels approximately , serving Coahoma, Quitman, Panola, Lafayette, Pontotoc, Lee, and Monroe Counties. West of Tupelo, it is concu ...
through Batesville,
Oxford Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
, and Pontotoc before reaching
Tupelo Tupelo , genus ''Nyssa'' , is a small genus of deciduous trees with alternate, simple leaves. It is sometimes included in the subfamily Nyssoideae of the dogwood family, Cornaceae, but is placed by other authorities in the family Nyssaceae. In ...
. At Tupelo, MS 6 separates from US 278 while US 278 overlaps US 45 south to New Wren. From New Wren, US 278 continues east through Amory before entering
Alabama (We dare defend our rights) , anthem = "Alabama (state song), Alabama" , image_map = Alabama in United States.svg , seat = Montgomery, Alabama, Montgomery , LargestCity = Huntsville, Alabama, Huntsville , LargestCounty = Baldwin County, Al ...
.


Alabama

US 278 enters Alabama between
Greenwood Springs, Mississippi Greenwood Springs is an unincorporated community in Monroe County, Mississippi. Greenwood Springs is located east of Amory on U.S. Route 278. History Greenwood Springs is named for the nearby mineral spring, which is in turn named for Thomas ...
, and
Sulligent, Alabama Sulligent is a city in Lamar County, Alabama, United States. As of the 2010 census, the population of the city was 1,927, down from its record high of 2,151 in 2000. From 1910-1950 and again in 2000, it was the largest community in Lamar County ...
. As in Georgia, this and all U.S routes are partnered with state routes; however, there are few instances throughout the state where the state route number is posted. From the Mississippi state line to Guin, US 278 is paired with
State Route 118 Route 118 or Highway 118 can refer to multiple roads: Argentina * National Route 118 Canada * British Columbia Highway 118 * New Brunswick Route 118 * Nova Scotia Highway 118 * Ontario Highway 118 * Prince Edward Island Route 118 Costa ...
. From
Hamilton Hamilton may refer to: People * Hamilton (name), a common British surname and occasional given name, usually of Scottish origin, including a list of persons with the surname ** The Duke of Hamilton, the premier peer of Scotland ** Lord Hamilt ...
to the Georgia state line, US 278 is paired with State Route 74. US 278 junctions with US 431 at Gadsden. The two routes overlap until they split at Attalla. US 278 overlaps US 43 between
Hamilton Hamilton may refer to: People * Hamilton (name), a common British surname and occasional given name, usually of Scottish origin, including a list of persons with the surname ** The Duke of Hamilton, the premier peer of Scotland ** Lord Hamilt ...
and Guin. Prior to the completion of Corridor X (Future
I-22 I22 or I 22 may refer to: * Interstate 22, a highway in the United States * Värmland Regiment, a Swedish infantry regiment; active 1816–1939 * Lapland Ranger Regiment The Lapland Ranger Regiment ( sv, Lapplands jägarregemente), designatio ...
), these two routes also overlapped US 78 between these two towns; eastbound US 78 traveled in the same direction as westbound US 278.


Georgia

In Atlanta, US 278 runs along Donald Lee Hollowell Parkway (
Bankhead Highway The Bankhead Highway was a United States cross-country automobile highway connecting Washington, D.C., and San Diego. The Bankhead Highway's beginnings can be traced back to 1916 when the Bankhead Highway Association was organized to promote the h ...
), North Avenue, briefly along Piedmont Road and Ponce de Leon Avenue. Outside
the Perimeter Interstate 285 (I-285) is an auxiliary Interstate Highway encircling Atlanta, Georgia, for . It connects the three major Interstate Highways to Atlanta: I-20, I-75, and I-85. Colloquially referred to as the Perimeter, it also carries unsi ...
, US 278 runs along Covington Highway. In
Lithonia, Georgia Lithonia (, ; AAVE: ) is a city in eastern DeKalb County, Georgia, United States. The city's population was 2,662 at the 2020 census. Lithonia is in the Atlanta metropolitan area. "Lithonia" means "city/town of stone". Lithonia is in the heart ...
, at the intersection with Turner Hill Road ( SR 124), US 278 merges with
I-20 Interstate 20 (I‑20) is a major east–west Interstate Highway in the Southern United States. I-20 runs beginning at an interchange with I-10 in Scroggins Draw, Texas, and ending at an interchange with I-95 in Florence, South Carolina. Between ...
for . It leaves I-20 at exit 90, in
Covington, Georgia Covington is a city in the U.S. state of Georgia and the seat of Newton County, and is part of the Atlanta metropolitan area. As of the 2010 Census, its population 14,113. History Covington was founded by European immigrants to the United Stat ...
. US 278 is co-signed with a state route for its entire length in Georgia, as are all U.S. Highways in the state. From the Alabama line into Lithia Springs, it is co-signed with SR 6. From Lithia Springs through Atlanta, it is merged with US 78/ SR 8. In Atlanta, US 278 merges further with other highways including SR 10 and US 23 before splitting off at Ponce de Leon Ave. and East Lake Road near Decatur. In
Avondale Estates Avondale Estates is a city in DeKalb County, Georgia, United States. The population was 2,960 at the 2010 census. It is part of the Atlanta metropolitan area and is near Decatur. History In the 1890s, lots were sold in the area, which was kno ...
, SR 12 is paired with US 278, all the way into
Thomson Thomson may refer to: Names * Thomson (surname), a list of people with this name and a description of its origin * Thomson baronets, four baronetcies created for persons with the surname Thomson Businesses and organizations * SGS-Thomson Mic ...
. There, US 278 merges with US 78/SR 10 to the South Carolina line.


South Carolina

After crossing the
Savannah River The Savannah River is a major river in the southeastern United States, forming most of the border between the states of South Carolina and Georgia. Two tributaries of the Savannah, the Tugaloo River and the Chattooga River, form the norther ...
, US 278 bypasses
North Augusta, South Carolina North Augusta is a city in Aiken and Edgefield counties in the U.S. state of South Carolina, on the north bank of the Savannah River. The population was 21,348 at the 2010 census. The city is included in the Central Savannah River Area (CSRA) ...
, en route to Beech Island and Johnson Crossroads. It then winds through a corner of the
Savannah River Site The Savannah River Site (SRS) is a U.S. Department of Energy (DOE) reservation in the United States in the state of South Carolina, located on land in Aiken, Allendale, and Barnwell counties adjacent to the Savannah River, southeast of August ...
. The route then continues onward through the towns of Allendale, Fairfax,
Hampton Hampton may refer to: Places Australia *Hampton bioregion, an IBRA biogeographic region in Western Australia *Hampton, New South Wales *Hampton, Queensland, a town in the Toowoomba Region *Hampton, Victoria Canada *Hampton, New Brunswick *Hamp ...
, Varnville, Ridgeland, and
Hardeeville Hardeeville is a city in Jasper and Beaufort counties in the U.S. state of South Carolina. The population was 7,473 as of the 2020 census, an increase of over 150% since 2010. Hardeeville is included within the Hilton Head Island-Bluffton-Beaufo ...
where it meets
I-95 Interstate 95 (I-95) is the main north–south Interstate Highway on the East Coast of the United States, running from US Route 1 (US 1) in Miami, Florida, to the Houlton–Woodstock Border Crossing between Maine and the Canadia ...
. US 278 shares the route between Ridgeland and Hardeeville with US 17. Upon reaching Hardeeville, the route heads eastward toward the
Atlantic The Atlantic Ocean is the second-largest of the world's five oceans, with an area of about . It covers approximately 20% of Earth's surface and about 29% of its water surface area. It is known to separate the " Old World" of Africa, Europe an ...
with major new developments lining the spine of the road from Hardeeville through Sun City and Bluffton before crossing over the bridge to
Hilton Head Island Hilton Head Island, sometimes referred to as simply Hilton Head, is a South Carolina Lowcountry, Lowcountry resort town and barrier island in Beaufort County, South Carolina, United States. It is northeast of Savannah, Georgia, and southwest of C ...
. US 278 ends at US 278 Business on the southern portion of Hilton Head Island, just outside
Sea Pines Plantation The Sea Pines Resort or Sea Pines is located in Sea Pines Plantation, a 5,200-acre private residential gated community located on the southern tip of the island which comprises the town of Hilton Head Island, South Carolina. Sea Pines is home to f ...
.


History

In 1954, US 278 was extended from
Guin, Alabama Guin is a city in Marion County, Alabama, Marion County, Alabama, United States. It incorporated in December 1889. At the 2020 United States Census, 2020 census, the population was 2,195. History Guin takes its name from a young country doctor, ...
, to
Augusta, Georgia Augusta ( ), officially Augusta–Richmond County, is a consolidated city-county on the central eastern border of the U.S. state of Georgia (U.S. state), Georgia. The city lies across the Savannah River from South Carolina at the head of its navig ...
. The extension was routed along US 43 from Guin to
Hamilton, Alabama Hamilton is a city in and the county seat of Marion County, Alabama, United States. It incorporated in 1896 and since 1980 has been the county's largest city, surpassing Winfield. It was previously the largest town in 1910. At the 2020 census, ...
, then over SR 74 to the Georgia state line. In Georgia, US 278 was routed over SR 6 to
Atlanta Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
and SR 12 to Augusta. A further extension from Augusta to
Jacksonboro, South Carolina Jacksonboro is an unincorporated community and census-designated place located in southeastern Colleton County, South Carolina, United States, along the west side of the Edisto River. Jacksonboro serves as a primary junction along U.S. Highway 17 ...
, in 1955 was denied by AASHO in 1955. In 1989, US 278 was rerouted through
Dallas, Georgia Dallas is a city in, and the county seat of, Paulding County, Georgia, United States. The estimated population, as of 2010, was 11,544. Dallas is a northwestern exurb of Atlanta, located approximately from the downtown area. It was named for G ...
; the former route through town was redesignated US 278 Byp. AASHTO approved another relocation through
Rockmart, Georgia Rockmart is a town in Polk County, Georgia, United States. Its population was 4,732 at the 2020 census. It developed as a railroad depot town when the Southern Railway built a station in the area. The community was incorporated in 1872, and wa ...
, in 1990; the former route through town became US 278 Bus. A third relocation the following year in
Cedartown, Georgia Cedartown is a city and the county seat of Polk County, Georgia. As of the 2020 census, the city had a population of 10,190. Cedartown is the principal city of and is included in the Cedartown, Georgia Micropolitan Statistical Area, which is i ...
, was also approved. Alabama rerouted a section of US 278 in Guin over a section of SR 118 in 1995. At the same time, South Carolina rerouted the highway in Ridgeland over US 17 and SC 88. Mississippi and Arkansas extended US 278 westward in 1997 from US 45 in
Nettleton, Mississippi Nettleton is a town in Lee and Monroe counties in Mississippi. The population was 1,935 at the 2020 census. Incorporated in 1888, the town was named after George Henry Nettleton, president of the Kansas City, Memphis and Birmingham Railroad (K ...
, to US 71 in
Wickes, Arkansas Wickes is a city in Polk County, Arkansas, Polk County, Arkansas, United States. The population was 754 at the 2010 census. Near Wickes is the Boggs Springs Youth Encampment of the American Baptist Association, a retreat of Missionary Baptist chur ...
. The following year, the highway was relocated on
Hilton Head Island, South Carolina Hilton Head Island, sometimes referred to as simply Hilton Head, is a South Carolina Lowcountry, Lowcountry resort town and barrier island in Beaufort County, South Carolina, United States. It is northeast of Savannah, Georgia, and southwest of C ...
; the former routing because US 278 Bus. Alabama relocated US 278 in Gadsden in 2000. Until early 2005, US 278 was only signed in Mississippi from the Alabama state line to US 45 west of Amory. US 278 in western Alabama was formerly routed through Haleyville via current SR 195 and SR 129. In 2014, Alabama relocated US 278 in Cullman.


Major intersections

;Arkansas : in
Wickes Wickes is a home improvement retailer and garden centre, based in the United Kingdom with more than 230 stores throughout the country. Its main business is the sale of supplies and materials, for homeowners and the building trade. It is listed ...
: north-northeast of Dierks. The highways travel concurrently to Dierks. : west of
Nashville Nashville is the capital city of the U.S. state of Tennessee and the seat of Davidson County. With a population of 689,447 at the 2020 U.S. census, Nashville is the most populous city in the state, 21st most-populous city in the U.S., and the ...
. The highways travel concurrently to Nashville. : in
Hope Hope is an optimistic state of mind that is based on an expectation of positive outcomes with respect to events and circumstances in one's life or the world at large. As a verb, its definitions include: "expect with confidence" and "to cherish ...
: in Hope : in Rosston. The highways travel concurrently through Rosston. : in Camden. The highways travel concurrently to west-northwest of East Camden. : in
Hampton Hampton may refer to: Places Australia *Hampton bioregion, an IBRA biogeographic region in Western Australia *Hampton, New South Wales *Hampton, Queensland, a town in the Toowoomba Region *Hampton, Victoria Canada *Hampton, New Brunswick *Hamp ...
: in
Warren A warren is a network of wild rodent or lagomorph, typically rabbit burrows. Domestic warrens are artificial, enclosed establishment of animal husbandry dedicated to the raising of rabbits for meat and fur. The term evolved from the medieval Angl ...
: east of Warren : in
Monticello Monticello ( ) was the primary plantation of Founding Father Thomas Jefferson, the third president of the United States, who began designing Monticello after inheriting land from his father at age 26. Located just outside Charlottesville, V ...
: west of Monticello : northwest of McGehee. The highways will travel concurrently to
Clarksdale, Mississippi Clarksdale is a city in and the county seat of Coahoma County, Mississippi, United States. It is located along the Sunflower River. Clarksdale is named after John Clark, a settler who founded the city in the mid-19th century when he establishe ...
. : in McGehee. US 65/US 278 travels concurrently to south-southeast of Lake Village. US 165/US 278 travels concurrently to Dermott. : in Lake Village. The highways travel concurrently to east of
Leland, Mississippi Leland is a city in Washington County, Mississippi, United States. It is located within the Mississippi Delta, on the banks of Deer Creek. The population was 4,481 at the 2010 census. It was once a railway town and had long been a center of cott ...
. ;Mississippi : east of Leland. US 61/US 278 travels concurrently to Clarksdale. : in Clarksdale. The highways travel concurrently through Clarksdale. : in Clarksdale : in Batesville : in Batesville : on the
Verona Verona ( , ; vec, Verona or ) is a city on the Adige River in Veneto, Northern Italy, Italy, with 258,031 inhabitants. It is one of the seven provincial capitals of the region. It is the largest city Comune, municipality in the region and the ...
Tupelo Tupelo , genus ''Nyssa'' , is a small genus of deciduous trees with alternate, simple leaves. It is sometimes included in the subfamily Nyssoideae of the dogwood family, Cornaceae, but is placed by other authorities in the family Nyssaceae. In ...
city line. The highways travel concurrently to north-northwest of New Wren. ;Alabama : in Guin. The highways travel concurrently to
Hamilton Hamilton may refer to: People * Hamilton (name), a common British surname and occasional given name, usually of Scottish origin, including a list of persons with the surname ** The Duke of Hamilton, the premier peer of Scotland ** Lord Hamilt ...
. : in Hamilton : in Cullman : in Cullman : south-southwest of
Summit A summit is a point on a surface that is higher in elevation than all points immediately adjacent to it. The topography, topographic terms acme, apex, peak (mountain peak), and zenith are synonymous. The term (mountain top) is generally used ...
: northwest of Attalla. The highways travel concurrently to Gadsden. : in Attalla. The highways travel concurrently through Attalla. : in Attalla : in Gadsden ;Georgia : in Cedartown. The highways travel concurrently through Cedartown. : in Lithia Springs. The highways travel concurrently to
Druid Hills Druid Hills is a community which includes both a census-designated place (CDP) in unincorporated DeKalb County, Georgia, United States, as well as a neighborhood of the city of Atlanta. The CDP's population was 14,568 at the 2010 census. The ...
. : in
Atlanta Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
: in Atlanta. The highways travel concurrently through Atlanta. : in Atlanta. US 29/US 278 travels concurrently to Druid Hills. : in Atlanta. The highways travel concurrently to Druid Hills. : in Belvedere Park : southeast of
Lithonia Lithonia (, ; AAVE: ) is a city in eastern DeKalb County, Georgia, United States. The city's population was 2,662 at the 2020 census. Lithonia is in the Atlanta metropolitan area. "Lithonia" means "city/town of stone". Lithonia is in the hear ...
. The highways travel concurrently to Covington. : south of
Social Circle In the social sciences, a social group can be defined as two or more people who interact with one another, share similar characteristics, and collectively have a sense of unity. Regardless, social groups come in a myriad of sizes and varieties ...
: in
Madison Madison may refer to: People * Madison (name), a given name and a surname * James Madison (1751–1836), fourth president of the United States Place names * Madison, Wisconsin, the state capital of Wisconsin and the largest city known by this ...
. The highways travel concurrently to northeast of Madison. : in
Barnett Barnett is both a surname and a masculine given name. Notable people with the name include: Surname Barnett is an Anglo-Saxon and Old French surname that came after the Norman Invasion.The original Anglo-Saxon spelling is baernet which means'the ...
: southeast of
Thomson Thomson may refer to: Names * Thomson (surname), a list of people with this name and a description of its origin * Thomson baronets, four baronetcies created for persons with the surname Thomson Businesses and organizations * SGS-Thomson Mic ...
. The highways travel concurrently to
Clearwater, South Carolina Clearwater is a census-designated place (CDP) in Aiken County, South Carolina. It lies near North Augusta, South Carolina, and is part of the Augusta, Georgia metropolitan area. Clearwater is located in historic Horse Creek Valley. The population ...
. : in
Harlem Harlem is a neighborhood in Upper Manhattan, New York City. It is bounded roughly by the Hudson River on the west; the Harlem River and 155th Street (Manhattan), 155th Street on the north; Fifth Avenue on the east; and 110th Street (Manhattan), ...
: in Augusta : in Augusta. The highways travel concurrently to Clearwater, South Carolina. : in Augusta. The highways travel concurrently to
North Augusta, South Carolina North Augusta is a city in Aiken and Edgefield counties in the U.S. state of South Carolina, on the north bank of the Savannah River. The population was 21,348 at the 2010 census. The city is included in the Central Savannah River Area (CSRA) ...
. ;South Carolina : in North Augusta : in Allendale. The highways travel concurrently through Allendale. : in Fairfax : in
Hampton Hampton may refer to: Places Australia *Hampton bioregion, an IBRA biogeographic region in Western Australia *Hampton, New South Wales *Hampton, Queensland, a town in the Toowoomba Region *Hampton, Victoria Canada *Hampton, New Brunswick *Hamp ...
. The highways travel concurrently through Hampton. : in Ridgeland. The highways travel concurrently to
Hardeeville Hardeeville is a city in Jasper and Beaufort counties in the U.S. state of South Carolina. The population was 7,473 as of the 2020 census, an increase of over 150% since 2010. Hardeeville is included within the Hilton Head Island-Bluffton-Beaufo ...
. : in
Hilton Head Island Hilton Head Island, sometimes referred to as simply Hilton Head, is a South Carolina Lowcountry, Lowcountry resort town and barrier island in Beaufort County, South Carolina, United States. It is northeast of Savannah, Georgia, and southwest of C ...
.


See also

*
U.S. Route 78 U.S. Route 78 (US 78) is an east–west United States highway that runs for 715 miles (1,151 km) from Memphis, Tennessee, to Charleston, South Carolina. From Byhalia, Mississippi to Birmingham, Alabama, US 78 is concurrent with Interstate 2 ...
* Special routes of U.S. Route 278


References


External links


U.S. Route 278 in South Carolina (Mapmikey's South Carolina Highways Page)


{{DEFAULTSORT:78-2 United States Numbered Highway System U.S. Highways in Mississippi